Your body
needs a VITAMIN
D·Nobile
to stay healthy

Dietary supplement with vitamin D that contributes to the normal function of the immune system, supports the cell division process, and aids in the normal absorption of calcium and phosphorus.

Vitamin D is a hormone produced in the skin as a result of exposure to the sun.
Only small amounts can also be taken in through the diet, especially through the intake of oils rich in polyunsaturated fats.



When is it used?

When Vitamin D values are not between 20 and 40 ng/mL, which is the
physiological range, is recommended supplementation¹.

The Plus of D·Nobile

Unique Vitamin D of plant
origin in Extra Virgin Oil of Cultivar Coratina Olives
(and NOT in seed oil) in 100 I.U. drops.

EVO oil protects the structure of Vitamin D from oxidation.
VITAMIN D
of plant origin and not synthetically produced, extract from LICHEN
(Cladonia rangiferina)
The richest
in polyphenols,
natural
antioxidants
that reduce
inflammation.

EVO oil
improves
Vitamin D absorption by chemical-physical affinity

Most effective formulation

Why ok 2000 I.U. drops?

Clinical studies have shown that Vitamin D is not fully absorbed in single administration.

25 (OH)D vs baseline (ng/mL)

Cumulative administered dose of cholecalciferol (x 1,000 IU)

Pharmacokinetics of different therapeutic patterns in vitamin D deficient patients.Orange line 10,000 I.U. daily, yellow line 50,000 I.U. weekly, brown line 100,000 I.U. biweekly (from Fassio et al.,2020, mod).

ARE VITAMIN D BOLUSES EFFECTIVE ?

Graph expressing
the hypothesis of a
threshold
extra-skeletal
effect of Vitamin D
and the effect of
boluses and daily
administration on
Vitamin D levels
and25(0HJD²

VITAMIN D UpDates Scientific review Download pdf

Levels of Vit.D with boles

Levels of Vit.D with daily amount

Levels 25(OH)D with boles

Levels 25(OH)D with daily amount

1 Drop = 100 I.U. -> ADJUSTABLE ACCORDING TO NEEDS

Can be used from the 3rd MONTH OF LIFE – Formulation permitted for pediatric use.

How to use

Adults: 20 drops a day taken as such during the mail meal

Children: from 3 to 12 months 4 drops a day (400 I.U.).

Ingredients:

Organic extra virgin olive oil, Vitamin D3 (cholecalciferol) from Lichen (Cladonia rangiferina (L.) Weber ex F.H. Wigg.), antioxidant: alpha-tocopherol.

Average content of
ingredients		Maximum daily dose
(20 drops equal to 0,66 g)
Vitamine D3 (cholecalciferol)50 mcg – 2000 U.I. (1000% VNR*)
*VNR: daily nutritional reference values for vitamins and
minerals for an average adult – Reg. UE 1169/2011

1 pack = 45 days of recommended daily dose therapy.

Frequently Asked Questions

+ Is D-NOBILE suitable for those following a vegan diet?
Yes, D-NOBILE is VeganOK certified as vitamin D comes from plant sources and not animal sources, therefore it is suitable for those following a vegan diet.
+ Are there any contraindications to taking D-NOBILE?
No interactions with drugs or therapies have been found.
+ Can D-NOBILE be taken during pregnancy or breastfeeding?
There are no contraindications to using the product during pregnancy or breastfeeding.

It is recommended to always take it under medical supervision.
+ At what time of day is it recommended to take D-NOBILE?
The most recommended time to take D-NOBILE is during a meal.

Vitamin D is fat-soluble and is better absorbed when combined with fats. Taking it during a meal that contains fats increases its bioavailability and facilitates its intestinal absorption, ensuring an adequate daily intake.
+ How long should D-NOBILE be taken?
D-NOBILE can also be taken continuously by performing cycles and each cycle can be repeated several times a year without particular problems.

It is always best to follow the instructions of your doctor or nutritionist, who can personalize the treatment based on the specific situation by monitoring the levels of Vitamin D.
+ From what age can you take D-NOBILE?
D-NOBILE can be taken starting from 3 months of age, with the daily dosage modulated according to individual needs and therapeutic indications.

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